Associate Scientist, Experimental & Molecular Pathology

Company: Takeda Pharmaceutical
Location: Boston
Posted on: November 12, 2024

Job Description:

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionAbout the role:At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as an Associate Scientist, Experimental & Molecular Pathology, in our Cambridge, Massachusetts office.OBJECTIVE / PURPOSEServe in an exciting role as a laboratory senior research associate that directly supports our cutting-edge drug discovery programs across our immune oncology pipeline. Develop & execute tissue slide-based assays & perform detailed analyses that drive drug development efforts through the identification of mechanisms of action, pharmacodynamic markers and predictive biomarker signatures. Interact with stakeholders across the department as well as external vendors. Be part of a rapidly evolving team that supports clinical development to move our most impactful programs forward in ways that meaningfully improve patient outcomes in the clinic.How you will contribute:ACCOUNTABILITIES -

• Develop and execute singleplex and multiplex immunohistochemistry/immunofluorescence assays.
• Conduct tissue image analyses on stained tissues from preclinical and clinical samples.
• Incorporate proper quality controls and best practices to produce high-quality work in an efficient manner.
• Complete all assigned laboratory duties in a timely-manner and effectively resolves technical issues.
• Communicate and collaborate effectively with departmental colleagues and external partners in a cross-functional, highly collaborative team environment.
• Appropriately document testing and record data in our electronic notebook.
• Responsibilities include -60% lab work and -40% collaboration with our oncology and GI teams and CROs.Minimum Requirements/Qualifications:
  • BS with 4-6+ years of experience in an academic and/or industry setting related to immunohistochemistry, target validation, mechanism of action, pharmacodynamic, and translational strategies across different therapeutic areas (including oncology, gastrointestinal and neurology).
  • Experience in automated IHC/IF assay development (Leica, Ventana, DAKO) and analysis of markers in human and animal tissue specimens is strongly preferred. Specifically, knowledge of Ventana IHC/IF staining platform is a plus.
  • Experience in image analysis (HALO and Visiopharm software) is a plus.
  • Knowledge of basic disease mechanisms and basic understanding of small molecules, antibody-based therapeutics and cell therapies mechanisms of action is a plus.
  • Excellent oral and written communication skills.
  • Ability to work within multi-disciplinary and matrixed teams.
  • Good fit with Takeda core values and leadership principles.
  • Right attitude (agile, curious, open-minded, "can-do" mindset).
  • Effective time management skills.Takeda Compensation and Benefits SummaryWe understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. -For Location:Boston, MAU.S. Base Salary Range:96,600.00 - 151,800.00The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.---The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. -U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. -EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsBoston, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull timeJob ExemptYes

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